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Covid-19 infection can affect heart directly: Experts

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Tribune News Service

Ludhiana, March 30

“Covid-19 infection can cause ‘myocarditis’ in the heart, which is an inflammation and is lethal. Though mostly, it affects lungs and causes pneumonia but a lot of cases have now come forward where it has affected heart lethally.”

Know Myocarditis

  • It is possible, but not yet established that myocarditis results from an immune system that lurches out of control, while trying to turn back the coronavirus, pumping out such excessive levels of chemicals called cytokines that cause inflammation that they damage the lungs and the heart alike.

Dr Virendar Sarwal, cardiothoracic and vascular surgeon, said a study led by Dr Zhibing Lu at Zhongnan Hospital of Wuhan University has found that 20 per cent of patients hospitalised with Covid-19, had some evidence of heart damage.

Many were not known to have underlying heart disease. But they often had abnormal electrocardiogram, in addition to elevated troponin levels, which sometimes soared to levels seen in patients with heart attacks, he asserted.

The risk of death in such patients is four-times more than in a normal patient and surprisingly most of the patients do not have history of heart disease, said Dr Sarwal. But so much about this new pathogen is unknown, and it is not yet clear what might cause heart damage following infection, he remarked.

Myocarditis can likely be caused either by the virus itself, or the body’s immune and inflammatory response to the virus, he said.

“It is possible, but not yet established that myocarditis results from an immune system that lurches out of control, while trying to turn back the coronavirus, pumping out such excessive levels of chemicals called cytokines that cause inflammation that they damage the lungs and the heart alike.”

The condition, called a cytokine storm, is more serious in older people and in people with underlying chronic diseases, said Dr Sarwal adding cytokines also promote blood coagulation and interfere with the body’s clot-busting system.

At the same time, fever caused by the virus increases the body’s metabolism and the heart’s output of blood. The result is that the patient’s heart must struggle with an increased demand for oxygen but a reduced supply, an imbalance that may lead to heart damage.

But doctors cannot rule out the possibility that the Covid directly damages heart.

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